Ontology highlight
ABSTRACT:
SUBMITTER: Yamaguchi H
PROVIDER: S-EPMC7300268 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Yamaguchi Hirohito H Taouk Ghina M GM
Frontiers in oncology 20200611
Yes-Associated Protein (YAP) and Transcriptional Co-activator with PDZ-binding Motif (TAZ) are the downstream effectors of the Hippo signaling pathway that play a crucial role in various aspects of cancer progression including metastasis. Metastasis is the multistep process of disseminating cancer cells in a body and responsible for the majority of cancer-related death. Emerging evidence has shown that cancer cells reprogram their metabolism to gain proliferation, invasion, migration, and anti-a ...[more]