Ontology highlight
ABSTRACT:
SUBMITTER: Hernandez-Lopez H
PROVIDER: S-EPMC7301541 | biostudies-literature | 2020 Jun
REPOSITORIES: biostudies-literature
Hernández-López Hiram H Leyva-Ramos Socorro S Azael Gómez-Durán Cesar Fernando CF Pedraza-Alvarez Alberto A Rodríguez-Gutiérrez Irving Rubén IR Leyva-Peralta Mario Alberto MA Razo-Hernández Rodrigo Said RS
ACS omega 20200601 23
Triazoles occupy an important position in medicinal chemistry because of their various biological activities. The structural features of 1,2,3-triazoles enable them to act as a bioisostere of different functional groups such as amide, ester, carboxylic acid, and heterocycle, being capable of forming hydrogen bonds and π-π interactions or coordinate metal ions with biological targets. In this work, the synthesis of 1,2,3-triazole derivatives via copper(I)-catalyzed azide-alkyne cycloaddition (CuA ...[more]