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Vaccines for COVID-19: The current state of play.


ABSTRACT: There is a strong consensus globally that a COVID-19 vaccine is likely the most effective approach to sustainably controlling the COVID-19 pandemic. An unprecedented research effort and global coordination has resulted in a rapid development of vaccine candidates and initiation of trials. Here, we review vaccine types, and progress with 10 vaccine candidates against SARS-CoV-2 - the virus that causes COVID-19 - currently undergoing early phase human trials. We also consider the many challenges of developing and deploying a new vaccine on a global scale, and recommend caution with respect to our expectations of the timeline that may be ahead.

SUBMITTER: Koirala A 

PROVIDER: S-EPMC7301825 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature

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Vaccines for COVID-19: The current state of play.

Koirala Archana A   Joo Ye Jin YJ   Khatami Ameneh A   Chiu Clayton C   Britton Philip N PN  

Paediatric respiratory reviews 20200618


There is a strong consensus globally that a COVID-19 vaccine is likely the most effective approach to sustainably controlling the COVID-19 pandemic. An unprecedented research effort and global coordination has resulted in a rapid development of vaccine candidates and initiation of trials. Here, we review vaccine types, and progress with 10 vaccine candidates against SARS-CoV-2 - the virus that causes COVID-19 - currently undergoing early phase human trials. We also consider the many challenges o  ...[more]

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