Dataset Information

Psychosocial factors and hospitalisations for COVID-19: Prospective cohort study of the general population.

ABSTRACT:

Objective

To examine the association of a range of psychosocial factors with hospitalisation for COVID-19.

Design

Prospective cohort study.

Setting

England.

Participants

UK Biobank comprises around half a million people who were aged 40 to 69 years at study induction between 2006 and 2010 when information on psychosocial factors and covariates were captured.

Main outcome measure

Hospitalisation for COVID-19 in England between 16th March and 26th April 2020 as provided by Public Health England.

Results

There were 908 hospitalisations for COVID-19 in an analytical sample of 431,051 people. In age- and sex-adjusted analyses, an elevated risk of COVID-19 was related to disadvantaged levels of education (odds ratio; 95% confidence interval: 2.05; 1.70, 2.47), income (2.00; 1.63, 2,47), area deprivation (2.20; 1.86, 2.59), occupation (1.39; 1.14, 1.69), psychological distress (1.58; 1.32, 1.89), mental health (1.50; 1.25, 1.79), neuroticism (1.19; 1.00, 1.42), and performance on two tests of cognitive function: verbal and numerical reasoning (2.66; 2.06, 3.34) and reaction speed (1.27; 1.08, 1.51). These associations were graded (p-value for trend <=0.038) such that effects were apparent across the full psychosocial continua. After mutual adjustment for these characteristics plus ethnicity, comorbidity, and lifestyle factors, only the relationship between lower cognitive function as measured using the reasoning test and a doubling in the risk of the infection remained (1.98; 1.38, 2.85).

Conclusion

A range of psychosocial factors revealed associations with hospitalisations for COVID-19 of which the relation with cognitive function was most robust to statistical adjustment.

SUBMITTER: Batty GD

PROVIDER: S-EPMC7302298 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature

ACCESS DATA

Publications

Psychosocial factors and hospitalisations for COVID-19: Prospective cohort study of the general population.

Batty G David GD Deary Ian J IJ Luciano Michelle M Altschul Drew M DM Kivimäki Mika M Gale Catharine R CR

medRxiv : the preprint server for health sciences 20200601

<h4>Objective</h4>To examine the association of a range of psychosocial factors with hospitalisation for COVID-19.<h4>Design</h4>Prospective cohort study.<h4>Setting</h4>England.<h4>Participants</h4>UK Biobank comprises around half a million people who were aged 40 to 69 years at study induction between 2006 and 2010 when information on psychosocial factors and covariates were captured.<h4>Main outcome measure</h4>Hospitalisation for COVID-19 in England between 16<sup>th</sup> March and 26<sup>t ...[more]

PMID: 32577689

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Dataset Information

Psychosocial factors and hospitalisations for COVID-19: Prospective cohort study of the general population.

Objective

Design

Setting

Participants

Main outcome measure

Results

Conclusion

Publications

Psychosocial factors and hospitalisations for COVID-19: Prospective cohort study of the general population.

Similar Datasets

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