Serum hepcidin level, iron metabolism and osteoporosis in patients with rheumatoid arthritis.
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ABSTRACT:
SUBMITTER: Sato H
PROVIDER: S-EPMC7303107 | biostudies-literature | 2020 Jun
REPOSITORIES: biostudies-literature
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Serum hepcidin level, iron metabolism and osteoporosis in patients with rheumatoid arthritis.
Sato Hiroe H Takai Chinatsu C Kazama Junichiro James JJ Wakamatsu Ayako A Hasegawa Eriko E Kobayashi Daisuke D Kondo Naoki N Nakatsue Takeshi T Abe Asami A Ito Satoshi S Ishikawa Hajime H Kuroda Takeshi T Suzuki Yoshiki Y Narita Ichiei I
Scientific reports 20200618 1
Hepcidin, a major regulator of iron metabolism and homeostasis, is regulated by inflammation. Recent studies have suggested that hepcidin and iron metabolism are involved in osteoporosis, and the aim of this study was to determine whether serum hepcidin levels are correlated with the degree of osteoporosis in patients with rheumatoid arthritis (RA). A total of 262 patients with RA (67.5 ± 11.4 years; 77.5% female) were enrolled. Serum iron, ferritin, and hepcidin levels were positively correlate ...[more]
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