Ontology highlight
ABSTRACT:
SUBMITTER: Moore TC
PROVIDER: S-EPMC7303926 | biostudies-literature | 2019 Sep
REPOSITORIES: biostudies-literature
Moore Timothy C TC Yang Alexander H AH Ogungbesan Olu O Hartkamp Remco R Iacovella Christopher R CR Zhang Qi Q McCabe Clare C
The journal of physical chemistry. B 20190828 36
Using molecular dynamics simulations, it is demonstrated that a partial coating of single-stranded DNA (ssDNA) reduces the penetration depth of a graphene nanoflake (GNF) into a phospholipid bilayer by attenuating the hydrophobic force that drives the penetration. As the GNF penetrates the bilayer, the ssDNA remains adsorbed to the GNF outside of the bilayer where it shields the graphene from the surrounding water. The penetration depth is found to be controlled by the amount of ssDNA coating th ...[more]