Ontology highlight
ABSTRACT:
SUBMITTER: Armstrong MK
PROVIDER: S-EPMC7304258 | biostudies-literature | 2019 Apr
REPOSITORIES: biostudies-literature
Journal of the American Chemical Society 20190403 15
The differential dihydrofunctionalization of terminal alkynes is accomplished through the reductive three-component coupling of terminal alkynes, aryl halides, and pinacolborane. The transformation results in hydrofunctionalization of both π-bonds of an alkyne in a single reaction promoted by cooperative action of a copper/palladium catalyst system. The differential dihydrofunctionalization reaction has excellent substrate scope and can be accomplished in the presence of esters, nitriles, alkyl ...[more]