Ontology highlight
ABSTRACT:
SUBMITTER: Shelley JR
PROVIDER: S-EPMC7304343 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Shelley Jennifer R JR Davidson Donald J DJ Dorin Julia R JR
Frontiers in immunology 20200612
Defensins are short, rapidly evolving, cationic antimicrobial host defence peptides with a repertoire of functions, still incompletely realised, that extends beyond direct microbial killing. They are released or secreted at epithelial surfaces, and in some cases, from immune cells in response to infection and inflammation. Defensins have been described as endogenous alarmins, alerting the body to danger and responding to inflammatory signals by promoting both local innate and adaptive systemic i ...[more]