Dataset Information

Appendiceal neoplasms and histological involvement of the mesoappendix: A case series.

ABSTRACT:

Introduction

Acute appendicitis is a common presentation to surgical departments, typically resulting in appendicectomy. Appendiceal tumours may not be visible intraoperatively, and are present in roughly 0.5-1% of specimens. Routine resection of the mesoappendix is not universally practiced, despite the mesoappendix being commonly involved in appendiceal tumours.This is a case series of the histological findings of 21 patients with appendiceal tumours, with consideration to tumour within the resected mesoappendix.

Methods

We reviewed the histology of 1344 patients undergoing laparoscopic appendicectomy over a 6-year period assessing for the presence of appendiceal tumours and resected mesoappendix.

Results

Twenty-one patients were found to have appendiceal tumours, with a mean maximum tumour dimension of 7.2 mm. Sixteen of these patients had simultaneous mesoappendix resection, of whom six (38%) were found to have direct or indirect tumour tissue within the mesoappendix.

Conclusion

Further evidence for routine removal of the mesoappendix, and the need for larger prospective studies to investigate for any survival benefit. We note the worrying trend of conservative management of acute appendicitis.

SUBMITTER: Rait JS

PROVIDER: S-EPMC7305355 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature

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Publications

Appendiceal neoplasms and histological involvement of the mesoappendix: A case series.

Rait Jaideep Singh JS McGillicuddy Joshua J Ajzajian Jirayr J

Annals of medicine and surgery (2012) 20200612

<h4>Introduction</h4>Acute appendicitis is a common presentation to surgical departments, typically resulting in appendicectomy. Appendiceal tumours may not be visible intraoperatively, and are present in roughly 0.5-1% of specimens. Routine resection of the mesoappendix is not universally practiced, despite the mesoappendix being commonly involved in appendiceal tumours.This is a case series of the histological findings of 21 patients with appendiceal tumours, with consideration to tumour withi ...[more]

PMID: 32577233

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Project description:Introduction The prevalence of appendiceal mucinous neoplasms (AMN) is about 0.2%–0.3% in the specimens of the appendix. The LAMN may appear unremarkable or can present as mucin-filled, crystally dilated tissues. The diagnosis of early-stage AMN is mostly incidental. It is of vital importance to know the features of LAMN for a timely diagnosis Case presentation A 46-year-old male came with the complaint of right iliac fossa swelling along with severe intensity pain and a single episode of vomiting. A 4 × 4cm tender, soft, cystic, mobile swelling was found upon the examination. Contrast-enhanced Computerized tomography (CT) scan of the abdomen revealed the appendix diameter of 10mm well-circumscribed cystic measuring 2.1 × 2 cm. Therefore, an open resection surgery was performed. The histopathological report revealed an intraepithelial lesion composed of flat mucinous epithelial cells having eosinophilic cytoplasm and low-grade nuclear atypia. Case discussion The AMNs are very rare neoplasms. The imaging modalities that can be diagnostic methods are abdominal and transvaginal ultrasonography (US), and abdominal computed tomography (CT). The low-grade features of the appendiceal mucinous neoplasms have the possibility of recurrence. The CT-scan findings of appendiceal lump>1.3cm along with cystic dilation and the calcification of the wall are the suggestive features of AMN. There is a high chance of dissemination and port site seeding in case of pneumoperitoneum. Conclusion This rare case suggests the significance of adding AMNs as a differential diagnosis in patients with abdominal pain and choosing the right approach to treat such patients to avoid complications. Highlights • The incidence of low-grade appendiceal mucinous neoplasms (LAMN) is quite low.• The diagnosis of the LAMN is incidental and should be included in the differentials for abdominal pain.• There should be proper examination along with appropriate investigations for patients presenting with abdominal pain.• The timely diagnosis and the appropriate management allow better outcomes.• Laparoscopy is preferred as compared to open resection.

Dataset Information

Appendiceal neoplasms and histological involvement of the mesoappendix: A case series.

Introduction

Methods

Results

Conclusion

Publications

Appendiceal neoplasms and histological involvement of the mesoappendix: A case series.

Similar Datasets

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