Ontology highlight
ABSTRACT:
SUBMITTER: Grillone K
PROVIDER: S-EPMC7305591 | biostudies-literature | 2020 Jun
REPOSITORIES: biostudies-literature
Grillone Katia K Riillo Caterina C Scionti Francesca F Rocca Roberta R Tradigo Giuseppe G Guzzi Pietro Hiram PH Alcaro Stefano S Di Martino Maria Teresa MT Tagliaferri Pierosandro P Tassone Pierfrancesco P
Journal of experimental & clinical cancer research : CR 20200620 1
The discovery of the role of non-coding RNAs (ncRNAs) in the onset and progression of malignancies is a promising frontier of cancer genetics. It is clear that ncRNAs are candidates for therapeutic intervention, since they may act as biomarkers or key regulators of cancer gene network. Recently, profiling and sequencing of ncRNAs disclosed deep deregulation in human cancers mostly due to aberrant mechanisms of ncRNAs biogenesis, such as amplification, deletion, abnormal epigenetic or transcripti ...[more]