Prognostic factors following complete resection of non-superior sulcus lung cancer invading the chest wall.

ABSTRACT:

Objectives

Locally advanced non-small-cell lung cancer (NSCLC) with chest wall invasion carries a high risk of recurrence and portends poor survival (30-40% and 20-50%, respectively). No studies have identified prognostic factors in patients who underwent R0 resection for non-superior sulcus NSCLC.

Methods

A retrospective review was conducted for all chest wall resections for NSCLC from 2004 to 2018. Patients with superior sulcus tumours, partial (<1 rib) or incomplete (R1/R2) resection or distant metastasis were excluded. Disease-free survival (DFS) and overall survival (OS) were estimated using the Kaplan-Meier method. Cox proportional hazards modelling was used to determine factors associated with DFS and OS.

Results

A total of 100 patients met inclusion criteria.

SUBMITTER: Jones GD 

PROVIDER: S-EPMC7305839 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature