Biofilm Formation by Streptococcus mutans is Enhanced by Indole via the Quorum Sensing Pathway.
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ABSTRACT:
SUBMITTER: Inaba T
PROVIDER: S-EPMC7308578 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
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Biofilm Formation by Streptococcus mutans is Enhanced by Indole via the Quorum Sensing Pathway.
Inaba Tomohiro T Obana Nozomu N Habe Hiroshi H Nomura Nobuhiko N
Microbes and environments 20200101 2
Interspecies interactions among oral microorganisms in the pathogenic biofilms causing dental caries have not yet been elucidated in detail. We herein demonstrated that indole and its derivatives induced biofilm formation by Streptococcus mutans. Indole is an intercellular signaling molecule that is produced by oral bacteria other than S. mutans. The amounts of biofilm and extracellular DNA were significantly increased by the addition of indole and 4-hydroxyindole (4-HI). An examination with quo ...[more]
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