Ontology highlight
ABSTRACT:
SUBMITTER: Jiang M
PROVIDER: S-EPMC7310007 | biostudies-literature | 2020 Jun
REPOSITORIES: biostudies-literature
Jiang Minlin M Chen Peixin P Wang Lei L Li Wei W Chen Bin B Liu Yu Y Wang Hao H Zhao Sha S Ye Lingyun L He Yayi Y Zhou Caicun C
Journal of hematology & oncology 20200622 1
Cytosolic DNA sensing, the cyclic GMP-AMP synthase-stimulator of interferon genes (cGAS-STING) pathway, is an important novel role in the immune system. Multiple STING agonists were developed for cancer therapy study with great results achieved in pre-clinical work. Recent progress in the mechanical understanding of STING pathway in IFN production and T cell priming, indicates its promising role for cancer immunotherapy. STING agonists co-administrated with other cancer immunotherapies, includin ...[more]