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Bacteriological profiles and drug susceptibility of Streptococcus isolated from conjunctival sac of healthy children.

ABSTRACT: BACKGROUND:To investigate bacterial flora and antibiotics susceptibility of Streptococcus pneumoniae isolated from the conjunctival sac of heathy children. METHODS:Bacteria were isolated from the secretions of conjunctival sac of healthy children between 2015 and 2018. Antimicrobial susceptibility of isolated S. pneumoniae strains were determined using microbroth dilution method. RESULTS:The sac secretions were collected from a total of 6440 children. 1409 samples presented bacterial growth, accounting for 21.8% of the samples. Among the 22 bacterial species isolated, 528 samples presented Gram-positive Staphylococcus spp. growth, accounting for 37.4% of the isolates, followed by Corynebacterium spp., counting for 30% of the isolates and Streptococcus pneumoniae, counting for 21.4% of the isolates. Antibiotics susceptibility tests showed that the majority of S. pneumoniae isolates were sensitive to most antibiotics tested. However, 72.8 and 81.2% of the isolates were resistant to erythromycin and tetracycline, respectively, and over 10% of them were resistant to gentamicin, tobramycin and rifampicin. CONCLUSIONS:The bacterial flora of healthy children is mainly consisted of Gram-positive bacteria belonging to Corynebacterium spp. and Streptococcus spp.; most of S. pneumoniae isolates were sensitive to antibiotics except erythromycin and tetracycline.

SUBMITTER: Ke R

PROVIDER: S-EPMC7310448 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature

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Bacteriological profiles and drug susceptibility of Streptococcus isolated from conjunctival sac of healthy children.

Ke Ruili R Zhang Min M Zhou Qin Q Yang Yunfei Y Shen Ruifen R Huang Huipin H Zhang Xiangrong X

BMC pediatrics 20200622 1

<h4>Background</h4>To investigate bacterial flora and antibiotics susceptibility of Streptococcus pneumoniae isolated from the conjunctival sac of heathy children.<h4>Methods</h4>Bacteria were isolated from the secretions of conjunctival sac of healthy children between 2015 and 2018. Antimicrobial susceptibility of isolated S. pneumoniae strains were determined using microbroth dilution method.<h4>Results</h4>The sac secretions were collected from a total of 6440 children. 1409 samples presented ...[more]

PMID: 32571257

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Dataset Information

Bacteriological profiles and drug susceptibility of Streptococcus isolated from conjunctival sac of healthy children.

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Bacteriological profiles and drug susceptibility of Streptococcus isolated from conjunctival sac of healthy children.

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