Rhes Tunnels: A Radical New Way of Communication in the Brain's Striatum?
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ABSTRACT:
SUBMITTER: Subramaniam S
PROVIDER: S-EPMC7310467 | biostudies-literature | 2020 Jun
REPOSITORIES: biostudies-literature
Publications
Rhes Tunnels: A Radical New Way of Communication in the Brain's Striatum?
BioEssays : news and reviews in molecular, cellular and developmental biology 20200401 6
Ras homolog enriched in the striatum (Rhes) is a striatal enriched protein that promotes the formation of thin membranous tubes resembling tunneling nanotubes (TNT)-"Rhes tunnels"-that connect neighboring cell and transport cargoes: vesicles and proteins between the neuronal cells. Here the literature on TNT-like structures is reviewed, and the implications of Rhes-mediated TNT, the mechanisms of its formation, and its potential in novel cell-to-cell communication in regulating striatal biology ...[more]
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