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Electro-oculography in bilateral optic neuropathy.


ABSTRACT:

Objective

Effect of bilateral, optic neuropathy on the function of retinal pigment epithelium has not been investigated extensively to date. This study aimed to determine the effect of bilateral, optic neuropathy on light peak:dark trough ratio, light peak and dark trough values of electro-oculography. Thirty-seven patients with a clinical diagnosis of bilateral optic neuropathy and 40 control subjects were recruited in this observational, cross-sectional study, carried out at the Neurophysiology unit, Teaching Hospital, Peradeniya, Sri Lanka. Pattern reversal visual evoked potentials, pattern electroretinography and electro-oculography were recorded in all of them.

Results

Twenty-four patients (64.9%) had reduced light peak:dark trough ratio values. The median light peak:dark trough ratio?±?inter quartile range of the patient group (1.50?±?0.4) was significantly lower than that of the controls (1.80?±?0.2), (p?

SUBMITTER: Dahanayake P 

PROVIDER: S-EPMC7310542 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature

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Electro-oculography in bilateral optic neuropathy.

Dahanayake Padmini P   Dassanayake Tharaka L TL   Pathirage Manoji M   Senanayake Saman S   Sedgwick Mike M   Weerasinghe Vajira V  

BMC research notes 20200612 1


<h4>Objective</h4>Effect of bilateral, optic neuropathy on the function of retinal pigment epithelium has not been investigated extensively to date. This study aimed to determine the effect of bilateral, optic neuropathy on light peak:dark trough ratio, light peak and dark trough values of electro-oculography. Thirty-seven patients with a clinical diagnosis of bilateral optic neuropathy and 40 control subjects were recruited in this observational, cross-sectional study, carried out at the Neurop  ...[more]

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