Ontology highlight
ABSTRACT:
SUBMITTER: Rodriguez S
PROVIDER: S-EPMC7310652 | biostudies-literature | 2020 Jun
REPOSITORIES: biostudies-literature
medRxiv : the preprint server for health sciences 20200616
Post-infectious anosmias typically follow death of olfactory sensory neurons (OSNs) with a months-long recovery phase associated with parosmias. While profound anosmia is the leading symptom associated with COVID-19 infection, many patients regain olfactory function within days to weeks without distortions. Here, we demonstrate that sterile induction of anti-viral type I interferon signaling in the mouse olfactory epithelium is associated with diminished odor discrimination and reduced odor-evok ...[more]