Animal Models Used in Hepatitis C Virus Research.
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ABSTRACT:
SUBMITTER: Berggren KA
PROVIDER: S-EPMC7312079 | biostudies-literature | 2020 May
REPOSITORIES: biostudies-literature
Publications
Animal Models Used in Hepatitis C Virus Research.
Berggren Keith A KA Suzuki Saori S Ploss Alexander A
International journal of molecular sciences 20200529 11
The narrow range of species permissive to infection by hepatitis C virus (HCV) presents a unique challenge to the development of useful animal models for studying HCV, as well as host immune responses and development of chronic infection and disease. Following earlier studies in chimpanzees, several unique approaches have been pursued to develop useful animal models for research while avoiding the important ethical concerns and costs inherent in research with chimpanzees. Genetically related hep ...[more]
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