Ontology highlight
ABSTRACT:
SUBMITTER: Gimeno A
PROVIDER: S-EPMC7312484 | biostudies-literature | 2020 May
REPOSITORIES: biostudies-literature
Gimeno Aleix A Mestres-Truyol Júlia J Ojeda-Montes María José MJ Macip Guillem G Saldivar-Espinoza Bryan B Cereto-Massagué Adrià A Pujadas Gerard G Garcia-Vallvé Santiago S
International journal of molecular sciences 20200527 11
Since the outbreak of the COVID-19 pandemic in December 2019 and its rapid spread worldwide, the scientific community has been under pressure to react and make progress in the development of an effective treatment against the virus responsible for the disease. Here, we implement an original virtual screening (VS) protocol for repositioning approved drugs in order to predict which of them could inhibit the main protease of the virus (M-pro), a key target for antiviral drugs given its essential ro ...[more]