Ontology highlight
ABSTRACT:
SUBMITTER: Chulpanova DS
PROVIDER: S-EPMC7312663 | biostudies-literature | 2020 Jun
REPOSITORIES: biostudies-literature
Chulpanova Daria S DS Kitaeva Kristina V KV Rutland Catrin S CS Rizvanov Albert A AA Solovyeva Valeriya V VV
International journal of molecular sciences 20200609 11
Recent advances in the development of new methods of cancer immunotherapy require the production of complex cancer animal models that reliably reflect the complexity of the tumor and its microenvironment. Mice are good animals to create tumor models because they are low cost, have a short reproductive cycle, exhibit high tumor growth rates, and can be easily genetically modified. However, the obvious problem of these models is the high failure rate observed in human clinical trials after promisi ...[more]