Ontology highlight
ABSTRACT:
SUBMITTER: Zhang H
PROVIDER: S-EPMC7312837 | biostudies-literature | 2020 May
REPOSITORIES: biostudies-literature
Zhang Hui H Brown R Dale RD Stenmark Kurt R KR Hu Cheng-Jun CJ
International journal of molecular sciences 20200526 11
Pulmonary hypertension (PH) is a life-threatening disease characterized by significant vascular remodeling and aberrant expression of genes involved in inflammation, apoptosis resistance, proliferation, and metabolism. Effective therapeutic strategies are limited, as mechanisms underlying PH pathophysiology, especially abnormal expression of genes, remain unclear. Most PH studies on gene expression have focused on gene transcription. However, post-transcriptional alterations have been shown to p ...[more]