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Occurrence and Timing of Subsequent Severe Acute Respiratory Syndrome Coronavirus 2 Reverse-transcription Polymerase Chain Reaction Positivity Among Initially Negative Patients.

ABSTRACT: Using data for 20 912 patients from 2 large academic health systems, we analyzed the frequency of severe acute respiratory syndrome coronavirus 2 reverse-transcription polymerase chain reaction test discordance among individuals initially testing negative by nasopharyngeal swab who were retested on clinical grounds within 7 days. The frequency of subsequent positivity within this window was 3.5% and was similar across institutions.

SUBMITTER: Long DR

PROVIDER: S-EPMC7314163 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature

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Occurrence and Timing of Subsequent Severe Acute Respiratory Syndrome Coronavirus 2 Reverse-transcription Polymerase Chain Reaction Positivity Among Initially Negative Patients.

Long Dustin R DR Gombar Saurabh S Hogan Catherine A CA Greninger Alexander L AL O'Reilly-Shah Vikas V Bryson-Cahn Chloe C Stevens Bryan B Rustagi Arjun A Jerome Keith R KR Kong Christina S CS Zehnder James J Shah Nigam H NH Weiss Noel S NS Pinsky Benjamin A BA Sunshine Jacob E JE

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20210101 2

Using data for 20 912 patients from 2 large academic health systems, we analyzed the frequency of severe acute respiratory syndrome coronavirus 2 reverse-transcription polymerase chain reaction test discordance among individuals initially testing negative by nasopharyngeal swab who were retested on clinical grounds within 7 days. The frequency of subsequent positivity within this window was 3.5% and was similar across institutions. ...[more]

PMID: 33501950

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