Association between ceramides and coronary artery stenosis in patients with coronary artery disease.

ABSTRACT:

Background

Coronary artery stenosis induces heart diseases including acute coronary syndrome (ACS). Some studies reported the ceramide species are associated with the ACS and major adverse cardia and cerebrovascular events (MACE). However, few studies investigated the association between plasma ceramide levels and the severity of stenosis, together with the onset of diseases. This aim of the present study was to investigate the association betweencertain ceramide species, coronary artery stenosis and acute coronary syndrome.

Methods

Five hundred fifty-three patients with definite or suspected CAD were recruited and received angiography. Subjects were assigned into 4 groups according to the severity of coronary artery stenosis. The measurements of 4 plasma ceramide species, n

SUBMITTER: Tu C 

PROVIDER: S-EPMC7315545 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature