Ontology highlight
ABSTRACT:
SUBMITTER: Putta RR
PROVIDER: S-EPMC7317090 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Frontiers in chemistry 20200619
Benzimidazoles are important <i>N</i>-heteroaromatic compounds with various biological activities and pharmacological applications. Herein, we present the first iron-catalyzed selective synthesis of 1,2-disubstituted benzimidazoles <i>via</i> acceptorless dehydrogenative coupling of primary alcohols with aromatic diamines. The tricarbonyl (η<sup>4</sup>-cyclopentadienone) iron complex catalyzed dehydrogenative cyclization, releasing water and hydrogen gas as by-products. The earth abundance and ...[more]