Ontology highlight
ABSTRACT:
SUBMITTER: Fleck N
PROVIDER: S-EPMC7318235 | biostudies-literature | 2020 Jun
REPOSITORIES: biostudies-literature
Fleck Nico N Heubach Caspar A CA Hett Tobias T Haege Florian R FR Bawol Pawel P PP Baltruschat Helmut H Schiemann Olav O
Angewandte Chemie (International ed. in English) 20200430 24
The understanding of biomolecular function is coupled to knowledge about the structure and dynamics of these biomolecules, preferably acquired under native conditions. In this regard, pulsed dipolar EPR spectroscopy (PDS) in conjunction with site-directed spin labeling (SDSL) is an important method in the toolbox of biophysical chemistry. However, the currently available spin labels have diverse deficiencies for in-cell applications, for example, low radical stability or long bioconjugation link ...[more]