Controlling timing and location in vaccines.
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ABSTRACT:
SUBMITTER: Irvine DJ
PROVIDER: S-EPMC7318960 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Publications
Controlling timing and location in vaccines.
Irvine Darrell J DJ Aung Aereas A Silva Murillo M
Advanced drug delivery reviews 20200626
Vaccines are one of the most powerful technologies supporting public health. The adaptive immune response induced by immunization arises following appropriate activation and differentiation of T and B cells in lymph nodes. Among many parameters impacting the resulting immune response, the presence of antigen and inflammatory cues for an appropriate temporal duration within the lymph nodes, and further within appropriate subcompartments of the lymph nodes- the right timing and location- play a cr ...[more]
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