Ontology highlight
ABSTRACT:
SUBMITTER: Edgar R
PROVIDER: S-EPMC7320720 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Mapping of reads to reference sequences is an essential step in a wide range of biological studies. The large size of datasets generated with next-generation sequencing technologies motivates the development of fast mapping software. Here, I describe URMAP, a new read mapping algorithm. URMAP is an order of magnitude faster than BWA with comparable accuracy on several validation tests. On a Genome in a Bottle (GIAB) variant calling test with 30× coverage 2×150 reads, URMAP achieves high accuracy ...[more]