Nitrosative Stress and Its Association with Cardiometabolic Disorders.
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ABSTRACT:
SUBMITTER: Perez-Torres I
PROVIDER: S-EPMC7321091 | biostudies-literature | 2020 May
REPOSITORIES: biostudies-literature
Publications
Nitrosative Stress and Its Association with Cardiometabolic Disorders.
Pérez-Torres Israel I Manzano-Pech Linaloe L Rubio-Ruíz María Esther ME Soto María Elena ME Guarner-Lans Verónica V
Molecules (Basel, Switzerland) 20200531 11
<b>:</b> Reactive nitrogen species (RNS) are formed when there is an abnormal increase in the level of nitric oxide (NO) produced by the inducible nitric oxide synthase (iNOS) and/or by the uncoupled endothelial nitric oxide synthase (eNOS). The presence of high concentrations of superoxide anions (O<sub>2</sub><sup>-</sup>) is also necessary for their formation. RNS react three times faster than O<sub>2</sub><sup>-</sup> with other molecules and have a longer mean half life. They cause irrevers ...[more]
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