Ontology highlight
ABSTRACT:
SUBMITTER: Okoth DA
PROVIDER: S-EPMC7321100 | biostudies-literature | 2020 Jun
REPOSITORIES: biostudies-literature
Okoth Dorothy A DA Hug Joachim J JJ Garcia Ronald R Spröer Cathrin C Overmann Jörg J Müller Rolf R
Molecules (Basel, Switzerland) 20200609 11
Myxobacteria represent an under-investigated source for biologically active natural products featuring intriguing structural moieties with potential applications, e.g., in the pharmaceutical industry. Sorangiadenosine and the here-discovered 2-hydroxysorangiadenosine are myxobacterial sesquiterpene-nucleosides with an unusual structural moiety, a bicyclic eudesmane-type sesquiterpene. As the biosynthesis of these rare terpene-nucleoside hybrid natural products remains elusive, we investigated se ...[more]