Ontology highlight
ABSTRACT:
SUBMITTER: Nakayama Y
PROVIDER: S-EPMC7322040 | biostudies-literature | 2020 Jun
REPOSITORIES: biostudies-literature
Nakayama Yukiteru Y Fujiu Katsuhito K Yuki Ryuzaburo R Oishi Yumiko Y Morioka Masaki Suimye MS Isagawa Takayuki T Matsuda Jun J Oshima Tsukasa T Matsubara Takumi T Sugita Junichi J Kudo Fujimi F Kaneda Atsushi A Endo Yusuke Y Nakayama Toshinori T Nagai Ryozo R Komuro Issei I Manabe Ichiro I
Proceedings of the National Academy of Sciences of the United States of America 20200608 25
Proper resolution of inflammation is vital for repair and restoration of homeostasis after tissue damage, and its dysregulation underlies various noncommunicable diseases, such as cardiovascular and metabolic diseases. Macrophages play diverse roles throughout initial inflammation, its resolution, and tissue repair. Differential metabolic reprogramming is reportedly required for induction and support of the various macrophage activation states. Here we show that a long noncoding RNA (lncRNA), <i ...[more]