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Characterization of Virus-specific Immune Response During Varicella Zoster Virus Encephalitis in a Young Adult.

ABSTRACT: An immunocompetent adult received corticosteroids for chest pain, which later was clinically found to be herpes zoster (HZ). She developed severe disease and rapid viral dissemination that elicited an exceptionally strong varicella zoster virus-specific B-cell and CD8 T-cell response. Clinicians should consider atypical HZ presentation prior to corticosteroid administration.

SUBMITTER: Sullivan NL

PROVIDER: S-EPMC7322817 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature

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Characterization of Virus-specific Immune Response During Varicella Zoster Virus Encephalitis in a Young Adult.

Sullivan Nicole L NL Eberhardt Christiane S CS Wieland Andreas A Akondy Rama S RS Yi Jumi J McElroy Anita K AK Ahmed Rafi R

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20190701 2

An immunocompetent adult received corticosteroids for chest pain, which later was clinically found to be herpes zoster (HZ). She developed severe disease and rapid viral dissemination that elicited an exceptionally strong varicella zoster virus-specific B-cell and CD8 T-cell response. Clinicians should consider atypical HZ presentation prior to corticosteroid administration. ...[more]

PMID: 30668661

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