Radiogenomics correlation between MR imaging features and mRNA-based subtypes in lower-grade glioma.
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ABSTRACT:
SUBMITTER: Liu Z
PROVIDER: S-EPMC7322922 | biostudies-literature | 2020 Jun
REPOSITORIES: biostudies-literature
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Radiogenomics correlation between MR imaging features and mRNA-based subtypes in lower-grade glioma.
BMC neurology 20200629 1
<h4>Background</h4>To investigate associations between lower-grade glioma (LGG) mRNA-based subtypes (R1-R4) and MR features.<h4>Methods</h4>mRNA-based subtyping was obtained from the LGG dataset in The Cancer Genome Atlas (TCGA). We identified matching patients (n = 145) in The Cancer Imaging Archive (TCIA) who underwent MR imaging. The associations between mRNA-based subtypes and MR features were assessed.<h4>Results</h4>In the TCGA-LGG dataset, patients with the R2 subtype had the shortest med ...[more]
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