Ontology highlight
ABSTRACT:
SUBMITTER: Dutta M
PROVIDER: S-EPMC7323713 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Dutta Munmee M Nakagawa Hidewaki H Kato Hiroaki H Maejima Kazuhiro K Sasagawa Shota S Nakano Kaoru K Sasaki-Oku Aya A Fujimoto Akihiro A Mateos Raúl Nicolás RN Patil Ashwini A Tanaka Hiroko H Miyano Satoru S Yasuda Takushi T Nakai Kenta K Fujita Masashi M
PeerJ 20200626
Esophageal squamous cell carcinoma (ESCC) is the predominant type of esophageal cancer in the Asian region, including Japan. A previous study reported mutational landscape of Japanese ESCCs by using exome sequencing. However, somatic structural alterations were yet to be explored. To provide a comprehensive mutational landscape, we performed whole genome sequencing (WGS) analysis of biopsy specimens from 20 ESCC patients in a Japanese population. WGS analysis identified non-silent coding mutatio ...[more]