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Effective control of SARS-CoV-2 transmission between healthcare workers during a period of diminished community prevalence of COVID-19.


ABSTRACT: Previously, we showed that 3% (31/1032)of asymptomatic healthcare workers (HCWs) from a large teaching hospital in Cambridge, UK, tested positive for SARS-CoV-2 in April 2020. About 15% (26/169) HCWs with symptoms of coronavirus disease 2019 (COVID-19) also tested positive for SARS-CoV-2 (Rivett et al., 2020). Here, we show that the proportion of both asymptomatic and symptomatic HCWs testing positive for SARS-CoV-2 rapidly declined to near-zero between 25th April and 24th May 2020, corresponding to a decline in patient admissions with COVID-19 during the ongoing UK 'lockdown'. These data demonstrate how infection prevention and control measures including staff testing may help prevent hospitals from becoming independent 'hubs' of SARS-CoV-2 transmission, and illustrate how, with appropriate precautions, organizations in other sectors may be able to resume on-site work safely.

SUBMITTER: Jones NK 

PROVIDER: S-EPMC7326489 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature

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Effective control of SARS-CoV-2 transmission between healthcare workers during a period of diminished community prevalence of COVID-19.

Jones Nick K NK   Rivett Lucy L   Sparkes Dominic D   Forrest Sally S   Sridhar Sushmita S   Young Jamie J   Pereira-Dias Joana J   Cormie Claire C   Gill Harmeet H   Reynolds Nicola N   Wantoch Michelle M   Routledge Matthew M   Warne Ben B   Levy Jack J   Córdova Jiménez William David WD   Samad Fathima Nisha Begum FNB   McNicholas Chris C   Ferris Mark M   Gray Jane J   Gill Michael M   Curran Martin D MD   Fuller Stewart S   Chaudhry Afzal A   Shaw Ashley A   Bradley John R JR   Hannon Gregory J GJ   Goodfellow Ian G IG   Dougan Gordon G   Smith Kenneth Gc KG   Lehner Paul J PJ   Wright Giles G   Matheson Nicholas J NJ   Baker Stephen S   Weekes Michael P MP  

eLife 20200619


Previously, we showed that 3% (31/1032)of asymptomatic healthcare workers (HCWs) from a large teaching hospital in Cambridge, UK, tested positive for SARS-CoV-2 in April 2020. About 15% (26/169) HCWs with symptoms of coronavirus disease 2019 (COVID-19) also tested positive for SARS-CoV-2 (Rivett et al., 2020). Here, we show that the proportion of both asymptomatic and symptomatic HCWs testing positive for SARS-CoV-2 rapidly declined to near-zero between 25th April and 24th May 2020, correspondin  ...[more]

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