Ontology highlight
ABSTRACT:
SUBMITTER: Reed EJ
PROVIDER: S-EPMC7326495 | biostudies-literature | 2020 May
REPOSITORIES: biostudies-literature
Reed Erin J EJ Uddenberg Stefan S Suthaharan Praveen P Mathys Christoph D CD Taylor Jane R JR Groman Stephanie Mary SM Corlett Philip R PR
eLife 20200526
Paranoia is the belief that harm is intended by others. It may arise from selective pressures to infer and avoid social threats, particularly in ambiguous or changing circumstances. We propose that uncertainty may be sufficient to elicit learning differences in paranoid individuals, without social threat. We used reversal learning behavior and computational modeling to estimate belief updating across individuals with and without mental illness, online participants, and rats chronically exposed t ...[more]