Ontology highlight
ABSTRACT:
SUBMITTER: Tobiasson V
PROVIDER: S-EPMC7326499 | biostudies-literature | 2020 Jun
REPOSITORIES: biostudies-literature
Tobiasson Victor V Amunts Alexey A
eLife 20200618
To understand the steps involved in the evolution of translation, we used <i>Tetrahymena thermophila</i>, a ciliate with high coding capacity of the mitochondrial genome, as the model organism and characterized its mitochondrial ribosome (mitoribosome) using cryo-EM. The structure of the mitoribosome reveals an assembly of 94-ribosomal proteins and four-rRNAs with an additional protein mass of ~700 kDa on the small subunit, while the large subunit lacks 5S rRNA. The structure also shows that the ...[more]