Ontology highlight
ABSTRACT:
SUBMITTER: Petersen ME
PROVIDER: S-EPMC7327223 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Petersen Melissa E ME Zhang Fan F Schupf Nicole N Krinsky-McHale Sharon J SJ Hall James J Mapstone Mark M Cheema Amrita A Silverman Wayne W Lott Ira I Rafii Michael S MS Handen Benjamin B Klunk William W Head Elizabeth E Christian Brad B Foroud Tatiana T Lai Florence F Rosas H Diana HD Zaman Shahid S Ances Beau M BM Wang Mei-Cheng MC Tycko Benjamin B Lee Joseph H JH O'Bryant Sid S
Alzheimer's & dementia (Amsterdam, Netherlands) 20200630 1
<h4>Introduction</h4>Previously generated serum and plasma proteomic profiles were examined among adults with Down syndrome (DS) to determine whether these profiles could discriminate those with mild cognitive impairment (MCI-DS) and Alzheimer's disease (DS-AD) from those cognitively stable (CS).<h4>Methods</h4>Data were analyzed on n = 305 (n = 225 CS; n = 44 MCI-DS; n = 36 DS-AD) enrolled in the Alzheimer's Biomarker Consortium-Down Syndrome (ABC-DS).<h4>Results</h4>Distinguishing MCI-DS from ...[more]