Ontology highlight
ABSTRACT:
SUBMITTER: Bressler J
PROVIDER: S-EPMC7328191 | biostudies-literature | 2020 Feb
REPOSITORIES: biostudies-literature
Bressler Jan J Marioni Riccardo E RE Walker Rosie M RM Xia Rui R Gottesman Rebecca F RF Windham B Gwen BG Grove Megan L ML Guan Weihua W Pankow James S JS Evans Kathryn L KL Mcintosh Andrew M AM Deary Ian J IJ Mosley Thomas H TH Boerwinkle Eric E Fornage Myriam M
The journals of gerontology. Series A, Biological sciences and medical sciences 20200201 3
Methylation levels measured at defined sites across the genome have recently been shown to be correlated with an individual's chronological age. Age acceleration, or the difference between age estimated from DNA methylation status and chronological age, has been proposed as a novel biomarker of aging. In this study, the cross-sectional association between two different measures of age acceleration and cognitive function was investigated using whole blood samples from 2,157 African American parti ...[more]