Cancer biomarker profiling using nanozyme containing iron oxide loaded with gold particles.

ABSTRACT: Nanozymes are nanomaterials with intrinsic magnetism and superparamagnetic properties. In the presence of an external magnet, nanozyme particles aggregate and redisperse without a foreign attraction. We evaluated the performances of nanozyme by changing the biosensing platforms and substituting other biological variants for a complete cancer assay detection. We investigated the expression of morphological variants in the transmission of signals using an electrochemical method. The signal responses, including signal enhancement with the nanozyme (Au-Fe₂O₃), showed a wide capturing range (greater than 80%, from 10² to 10⁵ cells ml^-1 in phosphate-buffered saline buffer, pH 7.4). The platform showed a fast response time within a dynamic ra

SUBMITTER: Akpe V 

PROVIDER: S-EPMC7328392 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature