Neutrophil: lymphocyte ratio is positively associated with subclinical diabetic cardiomyopathy.

ABSTRACT:

Background

Subclinical diabetic cardiomyopathy (DCM) occurs frequently in asymptomatic subjects with Type 2 diabetes mellitus (T2DM). The direct association between the immune system and DCM with effective biomarkers has been demonstrated in previous studies.

Methods

Five hundred seven subjects with T2DM were recruited from April 2018 to October 2019 and divided into T2DM with cardiac dysfunction (DCM) group and T2DM without cardiac dysfunction (non-DCM) group. The relationship between the quartiles of Neutrophil: lymphocyte ratio (NLR) and subclinical DCM was evaluated by using adjusted logistic regression models.(covariates: age, sex, BMI, duration of diabetes, and hyperlipidemia).

Results

Blood NLR was significantly upregulated in DCM group compared to non-DCM grou

SUBMITTER: Huang X 

PROVIDER: S-EPMC7329473 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature