Prevalence and risk factors for bone loss in Southern Chinese with rheumatic diseases.

ABSTRACT: BACKGROUD:This study is to explore the prevalence of different stages of bone loss and the potential risk factors in rheumatic patients. METHOD:A cross-sectional study recruits 1398 rheumatic patients and 302 healthy subjects. Demographic data, blood, and bone mineral density (BMD) tests are collected. Risk factors for bone loss in rheumatic patients are analyzed by logistic regression. RESULTS:(1) Rheumatic patients are consisted of 40.0% rheumatoid arthritis (RA), 14.7% systemic lupus erythematosus (SLE), 14.2% osteoarthritis (OA), 9.2% ankylosing spondylosis (AS), 7.9% gout, 7.0% primary Sjogren syndrome (pSS), 3.8% systemic sclerosis (SSc), and 3.2% mixed connective tissue disease (MCTD). (2) In male patients aged under 50 and premenopausal female patients, the bone mineral density score of AS (53.9%, P?< 0.001) and SLE (39.6%, P =?0.034) patients is lower than the healthy controls (18.2%). (3) Osteopenia and osteoporosis are more prevailing in male patients aged or older than 50 and postmenopausal female patients with RA (P 

SUBMITTER: Hu Z 

PROVIDER: S-EPMC7329556 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature