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Osteoblast/fibroblast coculture derived bioactive ECM with unique matrisome profile facilitates bone regeneration.


ABSTRACT: Highlights•Engineer bone bioactive ECM guided by cell-cell communication in cocultures.•The engineered ECM promotes cell adhesion, proliferation and osteogenic differentiation.•Biomaterials ornamented with the engineered ECM facilitates bone regeneration.•Comprehensive proteomic characterization of the unique ECM matrisome.

SUBMITTER: Li M 

PROVIDER: S-EPMC7330453 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature

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