Ontology highlight
ABSTRACT:
SUBMITTER: Glavind E
PROVIDER: S-EPMC7331244 | biostudies-literature | 2020 Jul
REPOSITORIES: biostudies-literature
Glavind Emilie E Gotthardt Daniel N DN Pfeiffenberger Jan J Sandahl Thomas Damgaard TD Bashlekova Teodora T Willemoe Gro Linno GL Hasselby Jane Preuss JP Weiss Karl Heinz KH Møller Holger Jon HJ Vilstrup Hendrik H Lee William M WM Schilsky Michael L ML Ott Peter P Grønbæk Henning H
Orphanet journal of rare diseases 20200702 1
<h4>Background</h4>Macrophages play a significant role in liver disease development and progression. The macrophage activation marker soluble (s)CD163 is associated with severity and prognosis in a number of different acute and chronic liver diseases but has been only sparsely examined in Wilson's disease (WD). We investigated sCD163 levels in patients with acute and chronic WD and hypothesized associations with liver disease phenotype and biochemical markers of liver injury.<h4>Methods</h4>We i ...[more]