Ontology highlight
ABSTRACT:
SUBMITTER: Li G
PROVIDER: S-EPMC7331460 | biostudies-literature | 2019 Sep
REPOSITORIES: biostudies-literature
Li GuoBin G Zhang Lan L Wang DongEn D AIQudsy Luban L Jiang Jean X JX Xu HuiYun H Shang Peng P
Journal of cellular biochemistry 20190520 9
The nature of muscle-bone crosstalk has been historically considered to be only mechanical, where the muscle is the load applier while bone provides the attachment sites. However, this dogma has been challenged with the emerging notion that bone and muscle act as secretory endocrine organs affect the function of each other. Biochemical crosstalk occurs through myokines such as myostatin, irisin, interleukin (IL)-6, IL-7, IL-15, insulin-like growth factor-1, fibroblast growth factor (FGF)-2, and ...[more]