Specific requirements for translation of biological research into clinical radiation oncology.
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ABSTRACT:
SUBMITTER: Krause M
PROVIDER: S-EPMC7332213 | biostudies-literature | 2020 Jul
REPOSITORIES: biostudies-literature
Publications
Specific requirements for translation of biological research into clinical radiation oncology.
Krause Mechthild M Alsner Jan J Linge Annett A Bütof Rebecca R Löck Steffen S Bristow Rob R
Molecular oncology 20200408 7
Radiotherapy has been optimized over the last decades not only through technological advances, but also through the translation of biological knowledge into clinical treatment schedules. Optimization of fractionation schedules and/or the introduction of simultaneous combined systemic treatment have significantly improved tumour cure rates in several cancer types. With modern techniques, we are currently able to measure factors of radiation resistance or radiation sensitivity in patient tumours; ...[more]
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