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Constructing an automatic diagnosis and severity-classification model for acromegaly using facial photographs by deep learning.


ABSTRACT: Due to acromegaly's insidious onset and slow progression, its diagnosis is usually delayed, thus causing severe complications and treatment difficulty. A convenient screening method is imperative. Based on our previous work, we herein developed a new automatic diagnosis and severity-classification model for acromegaly using facial photographs by deep learning on the data of 2148 photographs at different severity levels. Each photograph was given a score reflecting its severity (range 1~3). Our developed model achieved a prediction accuracy of 90.7% on the internal test dataset and outperformed the performance of ten junior internal medicine physicians (89.0%). The prospect of applying this model to real clinical practices is promising due to its potential health economic benefits.

SUBMITTER: Kong Y 

PROVIDER: S-EPMC7333291 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature

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Constructing an automatic diagnosis and severity-classification model for acromegaly using facial photographs by deep learning.

Kong Yanguo Y   Kong Xiangyi X   He Cheng C   Liu Changsong C   Wang Liting L   Su Lijuan L   Gao Jun J   Guo Qi Q   Cheng Ran R  

Journal of hematology & oncology 20200703 1


Due to acromegaly's insidious onset and slow progression, its diagnosis is usually delayed, thus causing severe complications and treatment difficulty. A convenient screening method is imperative. Based on our previous work, we herein developed a new automatic diagnosis and severity-classification model for acromegaly using facial photographs by deep learning on the data of 2148 photographs at different severity levels. Each photograph was given a score reflecting its severity (range 1~3). Our d  ...[more]

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