Ontology highlight
ABSTRACT:
SUBMITTER: Haimov E
PROVIDER: S-EPMC7335914 | biostudies-literature | 2020 Jul
REPOSITORIES: biostudies-literature
Biophysical journal 20200602 1
Keratin intermediate filaments form dynamic intracellular networks, which span the entire cytoplasm and provide mechanical strength to the cell. The mechanical resilience of the keratin intermediate filament network itself is determined by filament bundling. The bundling process can be reproduced in artificial conditions in the absence of any specific cross-linking proteins, which suggests that it is driven by generic physical forces acting between filaments. Here, we suggest a detailed model fo ...[more]