Ontology highlight
ABSTRACT:
SUBMITTER: Neng X
PROVIDER: S-EPMC7336761 | biostudies-literature | 2020 Jul
REPOSITORIES: biostudies-literature
Neng Xiao X Xiao Mao M Yuanlu Chen C Qinyan Li L Li Shu S Zhanyi Song S
Molecular genetics & genomic medicine 20200428 7
<h4>Background</h4>Benign childhood epilepsy with centrotemporal spikes (BECTS) or benign rolandic epilepsy is the most common epileptic syndrome in school-age children. Genetics is an important factor in BECTS pathogenesis, and <10 genes were associated with BECTS. This study aimed to identify novel genetic causes of BECTS.<h4>Methods</h4>We conducted whole-exome sequencing on a patient with BECTS and validated the findings by Sanger sequencing in a pedigree with three patients.<h4>Results</h4> ...[more]