Ontology highlight
ABSTRACT:
SUBMITTER: Seshadri SR
PROVIDER: S-EPMC7337963 | biostudies-literature | 2020 Jul
REPOSITORIES: biostudies-literature
Seshadri Suhas R SR Banarjee Chitra C Barros Mario H MH Fontanesi Flavia F
Nucleic acids research 20200701 12
Mitoribosome biogenesis is an expensive metabolic process that is essential to maintain cellular respiratory capacity and requires the stoichiometric accumulation of rRNAs and proteins encoded in two distinct genomes. In yeast, the ribosomal protein Var1, alias uS3m, is mitochondrion-encoded. uS3m is a protein universally present in all ribosomes, where it forms part of the small subunit (SSU) mRNA entry channel and plays a pivotal role in ribosome loading onto the mRNA. However, despite its cri ...[more]