Ontology highlight
ABSTRACT:
SUBMITTER: Kawanami D
PROVIDER: S-EPMC7338581 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Kawanami Daiji D Takashi Yuichi Y
Frontiers in pharmacology 20200630
Diabetic Kidney Disease (DKD) is the leading cause of end stage renal disease (ESRD) worldwide. Glucagon-like peptide 1 receptor agonists (GLP-1RAs) are now widely used in the treatment of patients with type 2 diabetes (T2D). A series of clinical and experimental studies demonstrated that GLP-1RAs have beneficial effects on DKD, independent of their glucose-lowering abilities, which are mediated by natriuresis, anti-inflammatory and anti-oxidative stress properties. Furthermore, GLP-1RAs have be ...[more]